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. 2023 May 18;12(10):3542. doi: 10.3390/jcm12103542

Table 1.

Gonadotoxicity risk of various oncologic treatments/regimens.

Gonadotoxicity Risk Treatment/Regimen
High
  • Conditioning chemotherapy for bone marrow transplantation

  • Total body irradiation

  • Alkylating agents

  • Pelvic radiotherapy

  • Brachytherapy for cervical cancer

Intermediate
  • Escalated therapy (e.g., BEACOPP) for Hodgkin’s lymphoma

  • Adjuvant chemotherapy agents for breast cancer

Low
  • Anti-metabolites

  • Vinca alkaloids

  • Anthracyclines

  • Topoisomerase inhibitors