Table 2.
Cases (n = 150) |
Controls (n = 450) |
p-Value | |
---|---|---|---|
FSH starting dose (UI) | 254.28 ± 84.38 | 267.41 ± 76.72 | 0.166 |
FSH total dose (UI) | 2837.5 [2025–3900] | 3000 [803–2008] | 0.395 |
Length of stimulation (days) | 11 [9–13] | 11 [9–12] | 0.301 |
E2 on day of hCG, pg/mL | 1518 [871–2391] | 1304 [2250–3900] | 0.040 |
No. oocytes retrieved | 5 [2–10] | 4 [2–7] | 0.048 |
Unsuccessful OPU, % | 8% (12/150) | 8.67% (39/450) | 0.800 |
OSI 1 | 1.78 [0.74–3.85] | 1.63 [0.73–3] | 0.315 |
MII oocytes | 4 [2–8] | 3 [2–6] | 0.067 |
MI oocytes | 1 [0–2] | 0 [0–1] | 0.182 |
MII rate 2, % | 72.36% (699/966) | 73.26% (1745/2382) | 0.386 |
Fertilization rate 2, % | 73.03% (547/749) | 68.89% (1280/1858) | 0.253 |
Cleavage rate 2, % | 37.47% (205/547) | 43.98% (563/1280) | 0.042 |
No. embryos transferred | 2 [1–2] | 1 [1–2] | 0.438 |
ET fresh cycles, % | 59.33% (89/150) | 64.00% (288/450) | 0.306 |
Implantation rate 2, % | 10.73% (22/205) | 17.93% (101/563) | 0.029 |
cCPR, % | 14.67% (22/150) | 22.44% (101/450) | 0.041 |
Notes: data are reported as mean (standard deviation) or median [25–75%] or % (ratio). Abbreviations: FSH, follicle-stimulating hormone; E2, serum estradiol; hCG, human Chorionic Gonadotropin; OPU, oocytes pick-up; OSI, ovarian sensitivity index; MII, metaphase II; MI, metaphase I; ET, embryo transfer; cCPR, cumulative clinical pregnancy rate. 1 Calculated as: no. retrieved oocytes/FSH total dose × 1000. 2 Calculated as follows: MII rate: (no. MII oocytes/no. retrieved oocytes); fertilization rate: (no. fertilized oocytes/no. inseminated oocytes); cleavage rate: (no. embryos/no. fertilized oocytes); implantation rate: (no. gestational sacs/no. transferred embryos).