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. 2023 May 18;24(10):8952. doi: 10.3390/ijms24108952

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Evaluation of advanced glycosylation end products signaling in the colonic mucosa of IBD patients. (A) Immunohistochemistry and quantification for AGE (brown). (B) Immunohistochemistry and quantification for RAGE. Nuclei are counterstained with hematoxylin; Original magnification 20×, scale bar: 25 μm. These images are representative of at least n = 4 subjects/groups. Data were analyzed by unpaired t-test. IBD: inflammatory bowel diseases group. (C) Quantitative Real-Time PCR for age receptor (AGER) expression. Red symbols indicated biopsies from healthy (red circle) and affected (red triangle) colonic mucosa of the same subjects.