Table 1.
Embryo transfer outcomes in infertile patients. The clinical outcomes of the studies for infertile women in this review are listed in the order they were discussed. The table compares the clinical outcomes for embryo transfers occurring with or without ERA use and PGT-A. ERA = endometrial receptivity array, PGT-A = pre-implantation genetic testing for aneuploidy.
| Retrospective Cohort Study: No Prior Genetic Screening [57] | |||
|---|---|---|---|
| Variable | Non-ERA Group | ERA Group | |
| Live birth rate | 39.7% | 50% | |
| Miscarriage rate | 10.7% | 5.6% | |
| Retrospective Cohort Studies: With Prior Genetic Screening | |||
| Study 1 [58] | |||
| Variable | Non-ERA Group | ERA Group (Receptive Only) | ERA Group (With Adjustment) |
| Pregnancy rate | 35.2% | 39% | 33.3% |
| Study 2 [59] | |||
| Variable | Non-ERA Group | ERA Group | |
| Implantation rate | 65% | 55.6% | |
| Pregnancy rate | 70% | 58.3% | |
| Study 3 [54]: | |||
| Variable | Non-ERA Group | ERA Group | |
| Live birth rate | 54.96% | 49.62% | |
| Positive pregnancy test rate | 74.50% | 69.17% | |
| Clinical pregnancy rate | 61.76% | 61.65% | |
| Miscarriage rate | 6.52% | 8.27% | |
| Prospective Cohort Study: With Prior Genetic Screening [55] | |||
| Variable | Non-ERA Group | ERA Group | |
| Live birth rate | 56.6% | 56.5% | |
| Randomized Controlled Trial: With Prior Genetic Screening [60] | |||
| Variable | Non-ERA Group (Fresh Embryo Transfer) | Non-ERA Group (FET) | ERA Group (pET) |
| Pregnancy rate (first embryo transfer) | 58.5% | 54.3% | 72.5% |
| Pregnancy rate (cumulative) | 80.7% | 79.7% | 93.6% |
| Live birth rate (first embryo transfer) | 45.7% | 42.4% | 56.2% |
| Live birth rate (cumulative) | 48.9% | 55.4% | 71.2% |
| Implantation rate | 38.6% | 43.2% | 57.3% |