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Effect of metformin, canagliflozin, metformin + canagliflozin, and quercetin on injured tubules with overt loss of epithelial cells (%). Periodic acid–Schiff-stained renal sections (200×) (A) injured tubules with overt loss of epithelial cells area percentage (B) in non-diabetic control rats and diabetic rats. Data are represented as mean ± SEM. Bars = 100 µm. * p < 0.05 vs. vehicle-treated diabetic rats, # p < 0.05 vs. non-diabetic control rats with normal renal function.
