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. 2023 May 20;24(10):9031. doi: 10.3390/ijms24109031

Table 2.

List of some of the AMPs that can be used in cancer therapeutic studies [158].

AMPs Source Significance Ref.
Poca A, Poca B and CyO4 Pombalia calceolaria Reduced the breast cancer cell up to 80% [185]
Aurein 1.2 Frog Litoria aurea Among 54 cancer cells, 52 are inhibited in NCI testing method [186]
Bmattacin2 Bombyx mori Disrupted A375 and HCT116 cancer cells [187]
Laterosporulin10 Brevibacillus sp. MCF-7, H1299, HEK293T, HT1080, and HeLa cancer cells were disrupted [188]
Dermaseptin-PD-1 and dermaseptin-PD-2 Phyllomedusine leaf frogs Growth of H157, PC-3, and U251 MG cancer cell was inhibited [189]
Scolopendrasin VII Centipede Reduction in the viability of leukaemia cells [190]
Myristoyl-CM4 Synthetic Activates caspase 9, caspase 3, and cleavage of Poly(ADP-ribose) polymerase (PARP) in breast cancer cells [191]
K4R2-Nal2-S1 Synthetic Binds with lung cancer cells and results in apoptosis [192]
VLL-28 Sulfolobus islandicus Inhibits murine and human tumour cells [193]
CopA3 Copris tripartitus Reduction in cell viability of gastric cancer cells [194]
Pardaxin Pardachirus armoratus Improved the activation of caspase-3 [195]