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ADA incidence by cohort
| Cohort | Dose | ADA-positive/Total Patients |
|---|---|---|
| 1 | IV 0.1 μg/kg | 0/1 |
| 2 | IV 0.3 μg/kg | 0/3 |
| 3 | IV 1 μg/kg | 0/3 |
| 4 | IV 3 μg/kg | 2/5 |
| 5 | SC 3 μg/kg | 2/3 |
| 6 | SC 10 μg/kg | 4/6 |
| 7 | SC 30 μg/kg | 3/4 |
| 8 | SC 10 then 30 μg/kg | 3/5 |
| 9 | SC 10 then 55 μg/kg | 2/5 |
| 10 | SC 5 and 20, then 60 μg/kg | 3/4 |
ADA, anti-drug-antibodies; IV, intravenous; SC, subcutaneous.
