Table 1.
Main characteristics of the studied population including patient, aneurysms and procedure-related characteristics as well as the main outcomes of the radiologic and clinical follow-up
| Patient characteristics | |||||||||
| No. of patients | 152 | ||||||||
| Patient age |
56 ± 12 years (22–81 years) |
||||||||
| Gender |
Female 112 (74%) |
Male 39 (26%) |
|||||||
| Comorbidities |
Arterial hypertension 88 (58%) |
DM II 13 (9%) |
Hypercholesterolemia 66 (43%) |
Declared smokers 59 (38.8%) |
|||||
| Aneurysm characteristics | |||||||||
| No. of aneurysms | 187 | ||||||||
| Aneurysm location |
Extradural ICA 21 (11.2%) |
Intradural ICA 119 (63.6%) |
ACA and ACOM 17 (9.1%) |
MCA 8 (4.3%) |
Vertebrobasilar 22 (11.8%) |
||||
| Morphology |
Saccular 156 (83.4%) |
Fusiform 19 (10.2%) |
Dissecting 4 (2.1%) |
Blister 8 (4.3%) |
|||||
| SAH |
Non-ruptured 161 (86.1%) |
Acute 6 (3.2%) |
Subacute (< 2 weeks) 2 (1.1%) |
Old (> 2 weeks) 14 (7.5%) |
|||||
|
Aneurysm size (maximum diameter) |
8.9 ± 7.6 mm (1–60 mm) |
||||||||
| Diameter of the parent artery |
Proximal 3.4 ± 0.9 mm (1–5.5 mm) |
Distal 3.0 ± 0.8 (1–5.5) |
|||||||
| Procedural details | |||||||||
| No. of procedures | 161 | ||||||||
| No. of implanted FDS | 170 | ||||||||
| Type of FDS |
FRED 86 (50.6%) |
FRED X 28 (16.5%) |
FRED Jr. 14 (8.2%) |
PED 11 (6.5%) |
PED Shield 4 (2.4%) |
PED Vantage 21 (12.4%) |
P48HPC 2 (1.2%) |
SILK 1 (0.6%) |
SURPASS 3 (1.8%) |
| Technique |
FDS only 113 (70.2%) |
FDS + coiling 45 (27.9%) |
FDS + other 3 (1.9%) |
||||||
| In-stent PTA |
Yes 8 (5.0%) |
No 153 (95%) |
|||||||
| Mean procedural time | 106 ± 50 min (40–269 min) | ||||||||
| Complications | |||||||||
| Total | 28 (17.4%) | ||||||||
|
Transient ND 19 (11.8%) |
Persistent ND at discharge 3 (1.9%) |
||||||||
| Thromboembolic | 24 (14.9%) | ||||||||
|
Intraoperative 12 |
Postoperative 12 |
||||||||
| Hemorrhagic | 4 (2.5%) | ||||||||
| Radiologic and clinical follow-up | |||||||||
| Occlusion rates at latest follow-up (RROC)6 |
I: Complete occlusion 124 (66.3%) |
II: Residual neck 28 (14.97%) |
III: Residual aneurysm 16 (8.56%) |
No follow-up available 19 (10.16%) |
|||||
| Clinical outcome at latest clinical follow-up (mRS) |
Good (mRS 0–1) 148 (97.4%) |
Poor (mRS ≥ 2) 2 (1.3%) |
Death (mRS 6) 2 (1.3%) |
||||||
Data indicated as mean ± standard deviation (minimum—maximum) or absolute number of cases (relative frequency in %). Relative frequency related to the number of patients (n = 152) or to the number of aneurysms (n = 187) for the “patients” or “aneurysm” sections, respectively
no. number, DM II diabetes mellitus type 2, ICA internal carotid artery, ACA anterior cerebral artery, ACOM anterior communicating artery, MCA middle cerebral artery, SAH subarachnoid hemorrhage, FDS flow diverter stent, PTA percutaneous transluminal angioplasty, ND neurological deficit, RROC Raymond-Roy occlusion classification, mRS modified Ranking Scale