Fig. 3. Landscape of co-mutations in UBTF mutant AML and survival analysis according to UBTF mutant status.

A Alignment of additional gene mutations in 52 UBTF-TD^pos patients. B Frequency distribution of additional gene mutations identified in UBTF-TD^pos vs. UBTF-TD^WT patients. C Variant allele frequencies (VAFs) of UBTF-TDs and frequent co-mutations (frequency of at least 10% in UBTF-mut patients). Solid bars indicate VAF median and IQR.