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. 2023 May 4;40(6):2886–2901. doi: 10.1007/s12325-023-02518-w

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© The Author(s) 2023, corrected publication 2023

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Fig. 2 — RAASi modifications after SZC initiation. Note: For the ZS-005 trial, patients were counted more than once if they required more than one RAASi adjustment so the total may exceed 100%. Rounding may cause differences of 1% or less among OPTIMIZE patient percentages. CKD chronic kidney disease; ESKD end-stage kidney disease; RAASi renin-angiotensin-aldosterone system inhibitors; SZC sodium zirconium cyclosilicate