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. 2023 Jan 10;7(11):2364–2374. doi: 10.1182/bloodadvances.2022008854

Figure 3.

Figure 3.

PD-1 expression on T-cells, T-regs and NK cells in patients with CML and in HD. PD-1 expression on T cells was not different between the MolR, TFR, or healthy donor (HD) groups either (A) as a percentage of T cells or (B) absolute counts. Similarly, there were no differences observed in (C) percentage of CD4+T cells, (D) absolute counts of PD-1+CD4+T cells, (E) percentage of CD8+T cells or (F) absolute counts of PD-1+CD8+T cells. (G) PD-1 expression as a percentage of T-regs was not different between the groups. (H) However, the absolute count of PD-1+T-regs was significantly higher in the patients in MolR group than in those in the TFR group. There was no difference in PD-1 expression on NK cells either (I) as a percentage of NK cells or (J) absolute counts. The Mann-Whitney test was used to compare 2 groups, whereas multiple comparisons were made using the Kruskal-Wallis test; alpha was set at 0.05 (adjusted for multiple comparisons).