Table 2.
GO analysis: biological process pathways.
| #term ID | Term description | Observed gene count | Background gene count | Strength | False discovery rate | Matching proteins in your network (IDs) | Matching proteins in your network (labels) |
|---|---|---|---|---|---|---|---|
| GO:0006750 | Glutathione biosynthetic process | 3 | 14 | 1.65 | 0.0383 | 9606.ENSP00000325548,9606.ENSP00000359258,9606.ENSP00000482639 | CNDP2,GCLM,MGST2 |
| GO:0006120 | Mitochondrial electron transport, nadh to ubiquinone | 5 | 49 | 1.33 | 0.0371 | 9606.ENSP00000322450,9606.ENSP00000354813,9606.ENSP00000356972,9606.ENSP00000362060,9606.ENSP00000419087 | NDUFV1,MT-ND5,NDUFS2,NDUFS5,NDUFB2 |
| GO:0042398 | Cellular modified amino acid biosynthetic process | 4 | 45 | 1.27 | 0.0409 | 9606.ENSP00000236959,9606.ENSP00000325548,9606.ENSP00000359258,9606.ENSP00000482639 | ATIC,CNDP2,GCLM,MGST2 |
| GO:1903214 | Regulation of protein targeting to mitochondrion | 4 | 47 | 1.25 | 0.0416 | 9606.ENSP00000335203,9606.ENSP00000340648,9606.ENSP00000346148,9606.ENSP00000425394 | ATPIF1,HUWE1,PRKAA1,ABLIM3 |
| GO:0032981 | Mitochondrial respiratory chain complex i assembly | 5 | 66 | 1.2 | 0.0371 | 9606.ENSP00000322450,9606.ENSP00000354813,9606.ENSP00000356972,9606.ENSP00000362060,9606.ENSP00000419087 | NDUFV1,MT-ND5,NDUFS2,NDUFS5,NDUFB2 |
| GO:1903747 | Regulation of establishment of protein localization to mitochondrion | 5 | 76 | 1.14 | 0.0371 | 9606.ENSP00000335203,9606.ENSP00000340648,9606.ENSP00000346148,9606.ENSP00000369127,9606.ENSP00000425394 | ATPIF1,HUWE1,PRKAA1,DNAJA1,ABLIM3 |
| GO:0002474 | Antigen processing and presentation of peptide antigen via mhc class i | 6 | 96 | 1.11 | 0.0371 | 9606.ENSP00000261023,9606.ENSP00000309474,9606.ENSP00000343405,9606.ENSP00000351314,9606.ENSP00000365402,9606.ENSP00000376141 | ITGAV,PSMD1,SEC24C,PSMB10,HLA-C,MFSD6 |
| GO:0042590 | Antigen processing and presentation of exogenous peptide antigen via mhc class i | 8 | 80 | 1.11 | 0.0371 | 9606.ENSP00000261023,9606.ENSP00000309474,9606.ENSP00000351314,9606.ENSP00000365402,9606.ENSP00000376141 | ITGAV,PSMD1,PSMB10,HLA-C,MFSD6 |
| GO:0033108 | Mitochondrial respiratory chain complex assembly | 6 | 102 | 1.09 | 0.0371 | 9606.ENSP00000322450,9606.ENSP00000345445,9606.ENSP00000354813,9606.ENSP00000356972,9606.ENSP00000362060,9606.ENSP00000419087 | NDUFV1,SAMM50,MT-ND5,NDUFS2,NDUFS5,NDUFB2 |
| GO:0019884 | Antigen processing and presentation of exogenous antigen | 8 | 182 | 0.96 | 0.0371 | 9606.ENSP00000255194,9606.ENSP00000261023,9606.ENSP00000292807,9606.ENSP00000309474,9606.ENSP00000343405,9606.ENSP00000351314,9606.ENSP00000365402,9606.ENSP00000376141 | AP3B1,ITGAV,AP2M1,PSMD1,SEC24C,PSMB10,HLA-C,MFSD6 |
| GO:0045333 | Cellular respiration | 7 | 158 | 0.96 | 0.0371 | 9606.ENSP00000217901,9606.ENSP00000280346,9606.ENSP00000322450,9606.ENSP00000354813,9606.ENSP00000356972,9606.ENSP00000362060,9606.ENSP00000419087 | IDH3G,DLAT,NDUFV1,MT-ND5,NDUFS2,NDUFS5,NDUFB2 |
| GO:0002478 | Antigen processing and presentation of exogenous peptide antigen | 7 | 174 | 0.92 | 0.0371 | 9606.ENSP00000261023,9606.ENSP00000292807,9606.ENSP00000309474,9606.ENSP00000343405,9606.ENSP00000351314,9606.ENSP00000365402,9606.ENSP00000376141 | ITGAV,AP2M1,PSMD1,SEC24C,PSMB10,HLA-C,MFSD6 |
| GO:0048872 | Homeostasis of number of cells | 7 | 204 | 0.85 | 0.0383 | 9606.ENSP00000258390,9606.ENSP00000269740,9606.ENSP00000294785,9606.ENSP00000335203,9606.ENSP00000337354,9606.ENSP00000340944,9606.ENSP00000361548 | DOCK10,SLC39A3,NCSTN,ATPIF1,LIPA,PTPN11,MPL |
| GO:0006091 | Generation of precursor metabolites and energy | 10 | 405 | 0.71 | 0.0371 | 9606.ENSP00000217901,9606.ENSP00000280346,9606.ENSP00000283646,9606.ENSP00000322450,9606.ENSP00000335203,9606.ENSP00000354813,9606.ENSP00000356972,9606.ENSP00000362060,9606.ENSP00000364490,9606.ENSP00000419087 | IDH3G,DLAT,RPIA,NDUFV1,ATPIF1,MT-ND5,NDUFS2,NDUFS5,ALDH4A1,NDUFB2 |
| GO:0007005 | Mitochondrion organization | 11 | 452 | 0.7 | 0.0371 | 9606.ENSP00000249442,9606.ENSP00000255194,9606.ENSP00000270538,9606.ENSP00000322450,9606.ENSP00000335203,9606.ENSP00000345445,9606.ENSP00000354813,9606.ENSP00000356972,9606.ENSP00000359258,9606.ENSP00000362060, 9606.ENSP00000419087 | MTX2,AP3B1,TIMM44,NDUFV1,ATPIF1,SAMM50,MT-ND5,NDUFS2,GCLM,NDUFS5,NDUFB2 |
| GO:0051223 | Regulation of protein transport | 13 | 617 | 0.64 | 0.0371 | 9606.ENSP00000263212,9606.ENSP00000335203,9606.ENSP00000338885,9606.ENSP00000340648,9606.ENSP00000340944,9606.ENSP00000346148,9606.ENSP00000347710,9606.ENSP00000369127,9606.ENSP00000370695,9606.ENSP00000377664,9606.ENSP00000384126,9606.ENSP00000425394, 9606.ENSP00000451261 | PPM1F,ATPIF1,C2CD2L,HUWE1,PTPN11,PRKAA1,OPHN1,DNAJA1,EXOC1,GAPVD1,LRRC32,ABLIM3,UBE2J1 |
| GO:1903827 | Regulation of cellular protein localization | 11 | 568 | 0.61 | 0.0416 | 9606.ENSP00000263212,9606.ENSP00000292807,9606.ENSP00000335203,9606.ENSP00000340648,9606.ENSP00000340944,9606.ENSP00000346148,9606.ENSP00000347710,9606.ENSP00000359000,9606.ENSP00000369127,9606.ENSP00000425394,9606.ENSP00000451261 | PPM1F,AP2M1,ATPIF1,HUWE1,PTPN11,PRKAA1,OPHN1,GBF1,DNAJA1,ABLIM3,UBE2J1 |
| GO:0032880 | Regulation of protein localization | 15 | 934 | 0.52 | 0.0371 | 9606.ENSP00000263212,9606.ENSP00000292807,9606.ENSP00000335203,9606.ENSP00000338885,9606.ENSP00000340648,9606.ENSP00000340944,9606.ENSP00000346148,9606.ENSP00000347710,9606.ENSP00000359000,9606.ENSP00000369127,9606.ENSP00000370695,9606.ENSP00000377664,9606.ENSP00000384126,9606.ENSP00000425394,9606.ENSP00000451261 | PPM1F,AP2M1,ATPIF1,C2CD2L,HUWE1,PTPN11,PRKAA1,OPHN1,GBF1,DNAJA1,EXOC1,GAPVD1,LRRC32,ABLIM3,UBE2J1 |
| GO:0001775 | Cell activation | 16 | 1075 | 0.49 | 0.0371 | 9606.ENSP00000258390,9606.ENSP00000261023,9606.ENSP00000263125,9606.ENSP00000294785,9606.ENSP00000301671,9606.ENSP00000309474,9606.ENSP00000319169,9606.ENSP00000331288,9606.ENSP00000340648,9606.ENSP00000340944,9606.ENSP00000351314,9606.ENSP00000357727,9606.ENSP00000359000,9606.ENSP00000359258,9606.ENSP00000361548,9606.ENSP0000036540 | DOCK10,ITGAV,PRKCQ,NCSTN,GHDC,PSMD1,PRMT5,TMEM173,HUWE1,PTPN11,PSMB10,S100A9,GBF1,GCLM,MPL,HLA-C |
| GO:0060341 | Regulation of cellular localization | 15 | 1027 | 0.48 | 0.046 | 9606.ENSP00000263212,9606.ENSP00000292807,9606.ENSP00000302486,9606.ENSP00000310649,9606.ENSP00000335203,9606.ENSP00000338885,9606.ENSP00000340648,9606.ENSP00000340944,9606.ENSP00000346148,9606.ENSP00000347184,9606.ENSP00000347710,9606.ENSP00000359000,9606.ENSP00000369127,9606.ENSP00000425394,9606.ENSP00000451261 | PPM1F,AP2M1,MAP2K1,BRSK1,ATPIF1,C2CD2L,HUWE1,PTPN11,PRKAA1,HTT,OPHN1,GBF1,DNAJA1,ABLIM3,UBE2J1 |
| GO:0140352 | Export from cell | 15 | 1028 | 0.48 | 0.046 | 9606.ENSP00000258787,9606.ENSP00000261023,9606.ENSP00000266085,9606.ENSP00000286371,9606.ENSP00000294785,9606.ENSP00000301671,9606.ENSP00000309457,9606.ENSP00000309474,9606.ENSP00000310649,9606.ENSP00000322628,9606.ENSP00000331288,9606.ENSP00000340648,9606.ENSP00000357727,9606.ENSP00000365402,9606.ENSP00000370695 | MYO1G,ITGAV,TIMP3,ATP1B3,NCSTN,GHDC,VPS41,PSMD1,BRSK1,ARL4D,TMEM173,HUWE1,S100A9,HLA-C,EXOC1 |
| GO:0016192 | Vesicle-mediated transport | 24 | 1805 | 0.44 | 0.0371 | 9606.ENSP00000255194,9606.ENSP00000258787,9606.ENSP00000261023,9606.ENSP00000266085,9606.ENSP00000281513,9606.ENSP00000292807,9606.ENSP00000294785, 9606.ENSP00000301671,9606.ENSP00000309457, 9606.ENSP00000309474,9606.ENSP00000310649,9606.ENSP00000322628,9606.ENSP00000331288,9606.ENSP00000340648,9606.ENSP00000343405,9606.ENSP00000347184,9606.ENSP00000347710,9606.ENSP00000357727, 9606.ENSP00000359000,9606.ENSP00000365402,9606.ENSP00000370695,9606.ENSP00000377664,9606.ENSP00000382379,9606.ENSP00000386911 | AP3B1,MYO1G,ITGAV,TIMP3,NBAS,AP2M1,NCSTN,GHDC,VPS41,PSMD1,BRSK1,ARL4D,TMEM173,HUWE1,SEC24C,HTT,OPHN1,S100A9,GBF1,HLA-C,EXOC1,GAPVD1,ANKRD28,ARHGAP25 |
| GO:0043085 | Positive regulation of catalytic activity | 19 | 1489 | 0.42 | 0.0409 | 9606.ENSP00000194530,9606.ENSP00000258390,9606.ENSP00000263125,9606.ENSP00000263212,9606.ENSP00000274376,9606.ENSP00000286371,9606.ENSP00000294785,9606.ENSP00000296585,9606.ENSP00000302486,9606.ENSP00000340454,9606.ENSP00000340944,9606.ENSP00000346148,9606.ENSP00000347710,9606.ENSP00000357727,9606.ENSP00000359258,9606.ENSP00000369127,9606.ENSP00000377664,9606.ENSP00000386911,9606.ENSP00000482639 | STRADB,DOCK10,PRKCQ,PPM1F,RASA1,ATP1B3,NCSTN,ITGA2,MAP2K1,RAP1GDS1,PTPN11,PRKAA1,OPHN1,S100A9,GCLM,DNAJA1,GAPVD1,ARHGAP25,MGST2 |
| GO:0051049 | Regulation of transport | 21 | 1776 | 0.39 | 0.0414 | 9606.ENSP00000261023,9606.ENSP00000263212,9606.ENSP00000286371,9606.ENSP00000296585,9606.ENSP00000302486,9606.ENSP00000309457,9606.ENSP00000310649,9606.ENSP00000335203,9606.ENSP00000338885,9606.ENSP00000340648,9606.ENSP00000340944,9606.ENSP00000346148,9606.ENSP00000347184,9606.ENSP00000347710,9606.ENSP00000348429,9606.ENSP00000369127,9606.ENSP00000370695,9606.ENSP00000377664,9606.ENSP00000384126,9606.ENSP00000425394,9606.ENSP00000451261 | ITGAV,PPM1F,ATP1B3,ITGA2,MAP2K1,VPS41,BRSK1,ATPIF1,C2CD2L,HUWE1,PTPN11,PRKAA1,HTT,OPHN1,ACSL5,DNAJA1,EXOC1,GAPVD1,LRRC32,ABLIM3,UBE2J1 |
| GO:0002376 | Immune system process | 27 | 2481 | 0.36 | 0.0371 | 9606.ENSP00000255194,9606.ENSP00000256412,9606.ENSP00000258390,9606.ENSP00000258787,9606.ENSP00000261023,9606.ENSP00000263125,9606.ENSP00000266542,9606.ENSP00000269740,9606.ENSP00000286371,9606.ENSP00000292807,9606.ENSP00000294785,9606.ENSP00000301671,9606.ENSP00000302486,9606.ENSP00000309474,9606.ENSP00000331288,9606.ENSP00000332247,9606.ENSP00000335203,9606.ENSP00000340648,9606.ENSP00000340944,9606.ENSP00000343405,9606.ENSP00000351314,9606.ENSP00000357727,9606.ENSP00000359000,9606.ENSP00000361548,9606.ENSP00000365402,9606.ENSP00000370695,9606.ENSP00000376141 | AP3B1,ADAMDEC1,DOCK10,MYO1G,ITGAV,PRKCQ,C1RL,SLC39A3,ATP1B3,AP2M1,NCSTN,GHDC,MAP2K1,PSMD1,TMEM173,ATP6V0A2,ATPIF1,HUWE1,PTPN11,SEC24C,PSMB10,S100A9,GBF1,MPL,HLA-C,EXOC1,MFSD6 |
| GO:0050790 | Regulation of catalytic activity | 25 | 2386 | 0.34 | 0.046 | 9606.ENSP00000194530,9606.ENSP00000258390,9606.ENSP00000263125,9606.ENSP00000263212,9606.ENSP00000266085,9606.ENSP00000274376,9606.ENSP00000286371,9606.ENSP00000294785,9606.ENSP00000296585,9606.ENSP00000302486,9606.ENSP00000309474,9606.ENSP00000335203,9606.ENSP00000340454,9606.ENSP00000340944,9606.ENSP00000346148,9606.ENSP00000347184,9606.ENSP00000347710,9606.ENSP00000357727,9606.ENSP00000359258,9606.ENSP00000369127,9606.ENSP00000377664,9606.ENSP00000381461,9606.ENSP00000386911,9606.ENSP00000409171,9606.ENSP00000482639 | STRADB,DOCK10,PRKCQ,PPM1F,TIMP3,RASA1,ATP1B3,NCSTN,ITGA2,MAP2K1,PSMD1,ATPIF1,RAP1GDS1,PTPN11,PRKAA1,HTT,OPHN1,S100A9,GCLM,DNAJA1,GAPVD1,PPME1,ARHGAP25,PLXNB2,MGST2 |
| GO:0009987 | Cellular process | 89 | 15024 | 0.09 | 0.0371 | 9606.ENSP00000194530,9606.ENSP00000216780,9606.ENSP00000217901,9606.ENSP00000236959,9606.ENSP00000242719,9606.ENSP00000248958,9606.ENSP00000249442,9606.ENSP00000255194,9606.ENSP00000258390, 9606.ENSP00000258787,9606.ENSP00000261023,9606.ENSP00000262947,9606.ENSP00000263125,9606.ENSP00000263212,9606.ENSP00000266085,9606.ENSP00000269740,9606.ENSP00000270538,9606.ENSP00000274376, 9606.ENSP00000280346,9606.ENSP00000281513,9606.ENSP00000283646,9606.ENSP00000286371,9606.ENSP00000291294,9606.ENSP00000292807,9606.ENSP00000294785,9606.ENSP00000296585,9606.ENSP00000301671,9606.ENSP00000302486,9606.ENSP00000309457,9606.ENSP00000309474,9606.ENSP00000310649,9606.ENSP00000312311,9606.ENSP00000312671,9606.ENSP00000319169,9606.ENSP00000322450,9606.ENSP00000322628,9606.ENSP00000325548,9606.ENSP00000331288,9606.ENSP00000332247,9606.ENSP00000335203,9606.ENSP00000337354,9606.ENSP00000338885,9606.ENSP00000340454,9606.ENSP00000340648,9606.ENSP00000340672,9606.ENSP00000340944,9606.ENSP00000342267,9606.ENSP00000343405,9606.ENSP00000345445,9606.ENSP00000346148,9606.ENSP00000347184,9606.ENSP00000347710,9606.ENSP00000348429,9606.ENSP00000350263,9606.ENSP00000351314,9606.ENSP00000354813,9606.ENSP00000356972,9606.ENSP00000357727,9606.ENSP00000359000,9606.ENSP00000359258,9606.ENSP00000359297, 9606.ENSP00000361245,9606.ENSP00000361548,9606.ENSP00000362060,9606.ENSP00000364490,9606.ENSP00000365402,9606.ENSP00000369127,9606.ENSP00000370695,9606.ENSP00000377664,9606.ENSP00000378563,9606.ENSP00000380837,9606.ENSP00000381461,9606.ENSP00000382379,9606.ENSP00000384126,9606.ENSP00000386911,9606.ENSP00000391249,9606.ENSP00000392270,9606.ENSP00000408526,9606.ENSP00000409171,9606.ENSP00000419027,9606.ENSP00000419087,9606.ENSP00000421566,9606.ENSP00000425394,9606.ENSP00000436049,9606.ENSP00000441365,9606.ENSP00000450436,9606.ENSP00000451261,9606.ENSP00000476767,9606.ENSP00000482639 | STRADB,PCK2,IDH3G,ATIC,RNF11,SDF2L1,MTX2,AP3B1,DOCK10,MYO1G,ITGAV,C19orf10,PRKCQ,PPM1F,TIMP3,SLC39A3,TIMM44,RASA1,DLAT,NBAS,RPIA,ATP1B3,PTGIR,AP2M1,NCSTN,ITGA2,GHDC,MAP2K1,VPS41,PSMD1,BRSK1,MRPL46,EHBP1L1,PRMT5,NDUFV1,ARL4D,CNDP2,TMEM173,ATP6V0A2,ATPIF1,LIPA,C2CD2L,RAP1GDS1,HUWE1,ARMCX3,PTPN11,SLC25A15,SEC24C,SAMM50,PRKAA1,HTT,OPHN1,ACSL5,PIGN,PSMB10,MT-ND5,NDUFS2,S100A9,GBF1,GCLM,NSDHL,HECTD3,MPL,NDUFS5,ALDH4A1,HLA-C,DNAJA1,EXOC1,GAPVD1,PFDN6,LSS,PPME1,ANKRD28,LRRC32,ARHGAP25,SEPT9,STRAP,IMPA1,PLXNB2,PCCB,NDUFB2,XPNPEP1,ABLIM3,EIF3M,MARVELD1,ALDH6A1,UBE2J1,FKBP8,MGST2 |