Table 1. .
Association Between COVID-19-Related Symptoms and Preinfection Vaccination Status
| Vaccinated Before Donation (n = 976) |
Not Vaccinated Before Donation (n = 282) |
Previously Infected (Anti-N+) (n = 92) |
Not Previously Infected (Anti-N−) (n = 1166) |
|||
|---|---|---|---|---|---|---|
| Presence of Symptoms up to 7 Days Post–Blood Donation | No. (%) | No. (%) | P Value | No. (%) | No. (%) | P Value |
| Cough | 573 (59) | 159 (56) | .49 | 46 (50) | 686 (59) | .098 |
| Headache | 425 (44) | 147 (52) | .011 | 33 (36) | 539 (46) | .055 |
| Muscle/body aches | 379 (39) | 152 (54) | <.0001 | 28 (30) | 503 (43) | .018 |
| Weakness/fatigue (malaise) | 396 (41) | 134 (48) | .038 | 34 (37) | 496 (42) | .30 |
| Sore throat | 416 (43) | 85 (30) | .0002 | 38 (41) | 463 (40) | .76 |
| Fever | 293 (30) | 130 (46) | <.0001 | 16 (17) | 407 (35) | .0006 |
| Chills | 276 (28) | 114 (40) | .0001 | 21 (23) | 369 (32) | .078 |
| Change in taste or smell | 111 (11) | 37 (13) | .42 | 7 (7.6) | 141 (12) | .20 |
| Shortness of breath/painful breathing | 73 (7.5) | 22 (7.8) | .86 | 4 (4.4) | 91 (7.8) | .23 |
| Diarrhea | 58 (5.9) | 27 (9.6) | .032 | 6 (6.5) | 79 (6.7) | .93 |
| Nausea and/or vomiting | 50 (5.1) | 24 (8.5) | .033 | 9 (9.8) | 65 (5.6) | .10 |
| New rash (unrelated to phlebotomy site) | 4 (0.4) | 1 (0.4) | 1.0 | 0 (0.0) | 5 (0.4) | 1.0 |
| Symptom count | .0079 | .0004 | ||||
| 0 | 154 (16) | 41 (14) | 27 (29) | 168 (14) | ||
| 1–3 | 416 (43) | 95 (34) | 36 (39) | 475 (41) | ||
| 4+ | 406 (42) | 146 (52) | 29 (32) | 523 (45) |
Significant P values indicated in bold.