Table 5.

Generalized Estimating Equation (GEE): contrasts of the combination of degree of NAFLD severity and time from baseline.

	Glucose		Insulin		Homa-IR		HbA1c
Contrast	β	95% CI	β	95% CI	β	95% CI	β	95% CI
(3 ms vs. t0) Mild	−7.75	−20.46; 4.96	−1.49	−5.58; 2.60	−0.45	−1.64; 0.74	0.91	−3.50; 5.32
(6 ms vs. t0) Mild	−8.85	−18.66; 0.96	−0.23	−3.83; 3.36	−0.23	−1.25; 0.79	−2.87	−6.02; 0.29
(9 ms vs. t0) Mild	−7.17	−19.98; 5.63	3.73	−2.77; 10.23	0.74	−1.16; 2.63	−5.35 *	−9.22; −1.48
(12 ms vs. t0) Mild	0.38	−26.48; 27.24	−6.41	−14.09; 1.27	−1.62	−4.01; 0.76	−4.23	−12.07; 3.61
(3 ms vs. t0) Moderate	−2.19	−9.09; 4.71	−4.09 *	−7.42; −0.76	−0.45	−1.64; 0.74	−2.41 *	−4.58; −0.23
(6 ms vs. t0) Moderate	0.64	−7.30; 8.58	−2.27	−6.16; 1.63	0.03	−1.33; 1.39	−3.90 **	−6.32; −1.48
(9 ms vs. t0) Moderate	−7.27	−15.61; 1.07	3.54	−7.72; 0.64	−1.16	−2.46; 0.14	−4.19 **	−6.82; −1.57
(12 ms vs. t0) Moderate	−7.02	−16.01; 1.97	−5.33 *	−9.59; −1.07	−1.58 *	−2.90; −0.26	−4.10 *	−6.92; −1.28
(3 ms vs. t0) Severe	−6.26	−20.23; 7.71	−3.05	−8.40; 2.30	−0.85	−2.81; 1.10	−2.79	−6.83; 1.25
(6 ms vs. t0) Severe	−6.25	−21.24; 8.74	−2.11	−8.16; 3.93	−0.78	−2.91; 1.36	−5.50 **	−9.65; −1.35
(9 ms vs. t0) Severe	−15.17 *	−30.57; 0.23	−2.67	−9.71; 4.38	−1.00	−3.40; 1.39	−7.34 **	−11.68;−3.00
(12 ms vs. t0) Severe	−16.74 *	−32.33; −1.15	7.42	−3.11; 17.96	1.26	−2.12; 4.6	−9.36 **	−13.71;−5.01

** p < 0.001, * p < 0.05. Homa-IR: Homeostatic Model Assessment for Insulin Resistance; HbA1c: Glycosylated Hemoglobin.