Table 2.
Viral neutralization. Neutralization of VSV-G, HIV-1CH58TF, HIV-1JRFL, or HIV-1AD8 pseudoviruses are shown as IC50 (average ± SD) of at least three independent experiments; IC50 values are in µM. CD4mc IC50.
| VSV-G Pseudovirus | HIV-1CH58TF | HIV-1JRFL | HIV-1AD8 | |
|---|---|---|---|---|
| DMSO | >100 | >100 | >100 | >100 |
| BNM-III-170 | >100 | 0.033 ± 0.01 | 13.49 ± 6.65 | 3.75 ± 1.3 |
| MCG-IV-210 | >100 | 3.46 ± 1.06 | >100 | >100 |
| TFH-I-070-A6 | >100 | 0.45 ± 0.09 | 67.24 ± 30 | 9.59 ± 3.4 |
| TFH-I-116-D1 | >100 | 0.065 ± 0.01 | 43.82 ± 16.6 | 4.8 ± 1.7 |
| ZXC-I-090 | >100 | 2.63 ± 0.5 | >100 | >100 |
| ZXC-I-092 | >100 | 0.75 ± 0.12 | 54.22 ± 22.8 | 34.05 ± 13.8 |
| DL-I-101 | >100 | 0.16 ± 0.03 | >100 | 10.21 ± 3.1 |
| DL-I-102 | >100 | 0.66 ± 0.25 | >100 | 87.02 ± 39 |