Mucin domain length |
120 amino acids |
350 amino acids |
250 amino acids |
Cysteine globular domains |
Three pairs |
Single pair |
Two pairs |
Cysteine in juxtamembrane region |
Absent |
Unpaired—involved in its homodimerization |
Absent |
N-Linked glycosylation sites |
Numerous |
Numerous |
Numerous |
Extracellular effective size range (kDa) |
90–170 |
90–170 |
90–170 |
Nonglycosylated N-terminal sequences |
Absent |
Present—high abundance of glutamic acid. |
Absent |
C-terminal binding pattern |
Mildly modified—which has functional implications for intracellular ligand binding |
Similar to podocalyxin |
Similar to endoglycan |