Figure 2.

Brain CHIKV titers in CD-1 mice infected IC with different CHIKV strains at different ages. Infectious virus levels in the brain of CD-1 mice intracranially infected with CHIKV strains SL15649 (A), AF15561 (B), and SM2013 (C) at PN2 or PN28; dotted black lines represent assay limit of detection; dashed purple line and dashed green line represent input virus amounts for PN2 and PN28 mice, respectively, normalized to the average brain weight at each age; solid horizontal purple and green lines represent data median; * p < 0.05, ** p < 0.01, *** p < 0.001, Sidak’s multiple comparisons test.