Table 2.
Crystallographic structures reported for members of the M1 family of metallopeptidases (Compiled from https://www.ebi.ac.uk/merops/cgi-bin/, accessed on 10 January 2023).
| Enzyme | Source | Crystallographic Codes of the Structures at Protein Data Bank (PDB) |
|---|---|---|
| aminopeptidase N | Plasmodium falciparum | 3EBG, 3EBH, 3EBI, 3Q43, 3Q44, 3T8V, 4J3B, 4K5L, 4K5M, 4K5N, 4K5O,4K5P, 4R5T, 4R5V, 4R5X, 4ZQT, 4ZW3, 4ZW5, 4ZW6, 4ZW7, 4ZW8, 4ZX3, 4ZX4, 4ZX5, 4ZX6, 5XM7, 5Y19, 5Y1H, 5Y1K, 5Y1Q, 5Y1R, 5Y1S, 5Y1T, 5Y1V, 5Y1W, 5Y1X, 6EA1, 6EA2, 6EAA, 6EAB, 6EE3, 6EE4, 6EE6, 6EED, 6SBQ, 6SBR |
| aminopeptidase N | Escherichia coli | 2DQ6, 2DQM, 2HPO, 2HPT, 2ZXG, 3B2P, 3B2X, 3B34, 3B37, 3B3B, 3KED, 3PUU, 3QJX,4Q4E, 4Q4I, 4XMT, 4XMU, 4XMV, 4XMW, 4XMX, 4XM2, 4XN1, 4XN2, 4XN4, 4XN5, 4XN7, 4XN8, 4XN9, 4XNA, 4XNB, 4XND, 4X03, 4X04, 4X05, 5MFR, 5MFS, 5MFT, 5Y01, 5YQ1, 5YQ2, 5YQB, 6G8B |
| aminopeptidase N | Homo sapiens | 4FYQ, 4FYR, 4FYS, 4FYT, 5LHD, 6AKT |
| aminopeptidase N | Sus scrofa | 4FSC, 4FKE, 4FKH, 4FKK, 4HOM, 4NAQ, 4NZ8, 4OU3 |
| ERAP 1 | Homo sapiens | 2XDT, 2YD0, 3MDJ, 3QNF, 3RJO, 6Q4R |
| ERAP 2 | Homo sapiens | 3SE6, 4E36, 4JBS, 5AB0, 5AB2, 5CU5, 5J6S, 5KIV |
| aminopeptidase A | Homo sapiens | 4KX7, 4KX8, 4KX9, 4KXA, 4KXB, 4KXC, 4KXD |
| leukotriene A4 hydrolase | Homo sapiens | 1G6W, 1H19, 1HS6, 1SQM, 2R59, 2VJ8, 3B7R, 3B7S, 3B7T, 3B7U, 3CHO, 3CHP, 3CHQ, 3CHR, 3CHS, 3FH5, 3FH7, 3FH8, 3FHE, 3FTS, 3FTU, 3FTV, 3FTW, 3FTX, 3FTY, 3FTZ, 3FU0, 3FU3, 3FU5, 3FU6, 3FUD, 3FUE, 3FUF, 3FUH, 3FUI, 3FUJ, 3FUK, 3FUL, 3FUM, 3FUN, 3U9W, 4DPR, 4L2L, 4MKT, 4Ms6, 4RSY, 4RVB, 5AEN, 5BPP, 5FWQ, 5N3W, 5NI2, 5NI4, 5NI6, 5NIA, 5NID, 5NIE, 6ENB, 6ENC, 6END |
| leukotriene A4 hydrolase (Saccharomyces cerevisiae) |
Saccharomyces cerevisiae (ATCC 204508/S288c) | 2XPY, 2XPZ, 2XQ0 |
| cold-active aminopeptidase (Colwellia psychrerythraea)-type peptidase | Colwellia psychrerythraea (34H/ATCC BAA-681) | 3CIA |
| tricorn interacting factor F3 | Thermoplasma acidophilum (ATCC 25905/DSM 1728/JCM 9062/NBRC 15155/AMRC-C165) | 1Z1W,1Z5H, 3Q7J |
| LePepA g.p. (Legionella pneumophila) | Legionella pneumophila | 5ZI5, 5ZI7, 5ZIE |
| TATA-binding protein-associated factor | Homo sapiens | 5FUR, 6MZC, 6MZL, 6MZM |
| IRAP (cystinil aminopeptidase) | Homo sapiens | 4P8Q, 4PJ6, 4Z7I, 5C97, 5MJ6 |