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. 2023 May 18;15(5):1524. doi: 10.3390/pharmaceutics15051524

Table 2.

Within- and between-run accuracy and precision (A & P) of the method in human plasma.

Analyte Nominal Concentration (ng/mL) Within-Run (n = 5) Between-Run (n = 15)
Mean Concentration (ng/mL) CV% Acc% Mean Concentration (ng/mL) CV% Acc%
rucaparib 100 87 6 87 96 8 96
255 250 7 98 259 7 101
1700 1708 7 100 1732 4 102
4250 4190 5 99 4289 4 101
niraparib 60 61 2 101 60 3 101
153 155 5 101 156 3 102
1020 1043 2 102 1044 2 102
2460 2442 2 96 2460 3 96
olaparib 140 139 3 99 143 4 102
357 356 2 100 358 3 100
2380 2361 3 99 2386 3 100
5950 5802 3 98 5810 3 98

Acc%, percentage of accuracy; CV%, coefficient of variation; n, number of replicates.