Table 5.
Within- and between-run A & P of the method in DBS.
| Analyte | Nominal Concentration (ng/mL) | Within-Run (n = 5) | Between-Run (n = 15) | ||||
|---|---|---|---|---|---|---|---|
| Mean Concentration (ng/mL) | CV% | Acc% | Mean Concentration (ng/mL) | CV% | Acc% | ||
| rucaparib | 100 | 95 | 6 | 95 | 96 | 5 | 96 |
| 255 | 255 | 3 | 100 | 258 | 3 | 101 | |
| 1700 | 1784 | 3 | 105 | 1761 | 3 | 104 | |
| 4250 | 4402 | 4 | 104 | 4353 | 5 | 102 | |
| niraparib | 60 | 60 | 3 | 101 | 59 | 4 | 98 |
| 153 | 149 | 2 | 98 | 149 | 3 | 97 | |
| 1020 | 1026 | 3 | 101 | 1009 | 3 | 99 | |
| 2460 | 2483 | 3 | 97 | 2418 | 3 | 95 | |
| olaparib | 140 | 132 | 2 | 94 | 140 | 5 | 100 |
| 357 | 338 | 2 | 95 | 350 | 4 | 98 | |
| 2380 | 2373 | 2 | 100 | 2376 | 3 | 100 | |
| 5950 | 5859 | 1 | 98 | 5918 | 3 | 99 | |
Acc%, percentage of accuracy; CV%, coefficient of variation; n, number of replicates.