Table 1.
Patient baseline characteristics with regard to sex.
| Characteristics | All (n = 737) |
Male (n = 484) |
Female (n = 253) |
p-Value |
|---|---|---|---|---|
| Basic Conditions | ||||
| Age [years] | 63 ± 15 | 63 ± 15 | 63 ± 16 | 0.7029 |
| Body mass index [kg/m2] | 28 ± 7 | 28 ± 7 | 27 ± 7 | 0.0062 |
| Severity on Sepsis Onset (Day 1) | ||||
| SOFA score | 10 ± 4 | 10 ± 4 | 9 ± 4 | 0.0636 |
| APACHE II-score | 22 ± 7 | 22 ± 7 | 22 ± 7 | 0.4484 |
| Use of vasopressor [%] | 70 | 69 | 72 | 0.4433 |
| Mechanical ventilation [%] | 87 | 87 | 87 | 0.9973 |
| Renal replacement therapy [%] | 10 | 11 | 9 | 0.5351 |
| Comorbidities [%] | ||||
| Arterial hypertension | 53 | 53 | 53 | 0.8619 |
| COPD | 15 | 16 | 12 | 0.1050 |
| Bronchial asthma | 2 | 2 | 3 | 0.3601 |
| Renal dysfunction | 10 | 11 | 8 | 0.1156 |
| NIDDM | 8 | 10 | 5 | 0.0206 |
| IDDM | 10 | 11 | 8 | 0.2232 |
| Chronic liver disease | 6 | 6 | 4 | 0.2527 |
| History of myocardial infarction | 6 | 7 | 4 | 0.0859 |
| History of stroke | 5 | 6 | 5 | 0.5533 |
| History of cancer | 14 | 15 | 12 | 0.3671 |
| Medication on Sepsis Onset [%] | ||||
| Statins | 23 | 26 | 19 | 0.0234 |
| Beta-blocker | 37 | 37 | 36 | 0.9559 |
| ACE inhibitor | 29 | 32 | 23 | 0.0097 |
| Bronchodilator | 10 | 10 | 10 | 0.8481 |
| Diuretics | 33 | 35 | 30 | 0.2007 |
| Anticoagulation during the last 6 months | 26 | 27 | 23 | 0.2449 |
| Recent Surgical History [%] | ||||
| Elective surgery | 27 | 26 | 30 | |
| Emergency surgery | 52 | 53 | 50 | 0.5379 |
| No surgery | 21 | 21 | 20 | |
| Site of Infection [%] | ||||
| Lung | 63 | 67 | 56 | |
| Abdomen | 19 | 17 | 22 | |
| Bone or soft tissue | 4 | 3 | 5 | |
| Surgical wound | 2 | 1 | 2 | 0.0838 |
| Urogenital | 2 | 2 | 4 | |
| Primary bacteremia | 6 | 6 | 5 | |
| Other | 4 | 4 | 6 |