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. 2023 May 15;13(5):836. doi: 10.3390/jpm13050836

Table 2.

Disease severity of patients with sepsis with regard to sex.

Characteristics All
(n = 737)
Male
(n = 484)
Female
(n = 253)
p-Value
Sepsis Severity
SOFA score 7.2 ± 3.7 7.4 ± 3.6 6.9 ± 3.8 0.0265
Days in septic shock 1 (0, 2) 0 (0, 2) 1 (0, 2) 0.1087
ICU length of stay 21 ± 16 20 ± 15 21 ± 19 0.6748
Hospital length of stay 39 ± 29 40 ± 30 37 ± 27 0.5416
Inflammatory Values
Leukocytes [1000/µL] 13.2 ± 5 13.1 ± 5.1 13.6 ± 4.9 0.1291
C-reactive protein [mg/L] (n = 380) 150.9 ± 85.7 153.9 ± 86,2 144 ± 84.3 0.3088
Procalcitonin [ng/dL] (n = 657) 1 (0.3, 3.4) 1 (0.3, 3.7) 0.8 (0.3, 2.8) 0.1571
Respiratory Values
SOFA respiratory subscore 2.0 ± 0.8 2.0 ± 0.8 1.9 ± 0.8 0.0091
Ventilated days 11 ± 8 11 ± 8 11 ± 9 0.2803
Patients with mechanical ventilation [%] 94 94 93 0.4787
Ventilation days/observation days [%] 68 ± 32 69 ± 31 66 ± 32 0.2674
Coagulation
SOFA coagulation subscore 0 (0, 0.5) 0 (0, 0.5) 0 (0, 0.5) 0.2398
Thrombocytes [1000/µL] 292 ± 150 293 ± 154 290 ± 141 0.7498
Liver Values
SOFA hepatic subscore 0 (0, 0.4) 0 (0, 0.5) 0 (0, 0.3) 0.1423
Bilirubin [mg/dL] 0.6 (0.4, 1.1) 0.7 (0.5, 1.2) 0.5 (0.4, 0.9) <0.001
AST [IU/L] (n = 483) 57 (35, 112) 58 (35, 112) 56 (32, 110) 0.8264
ALT [IU/L] (n = 713) 46 (23, 92) 47 (23, 88) 43 (22, 100) 0.3322
Cardiovascular Values
SOFA cardiovascular subscore 1.6 ± 1 1.6 ± 1 1.7 ± 1.1 0.7080
Vasopressor days 4 (1, 8) 4 (2, 8) 4 (1, 8) 0.9163
Patients with vasopressor treatment [%] 81 81 82 0.6856
Vasopressor days/observation days [%] 29 (11, 57) 29 (11, 56) 31 (11, 57) 0.5938
Central Nervous System
SOFA central nervous system 2.1 ± 1.1 2.1 ± 1.1 2.1 ± 1.1 0.9434
Glasgow Coma Scale (GCS) 10 ± 3 10 ± 3 10 ± 3 0.9965
Renal Values
SOFA renal subscore 0.2 (0, 1.2) 0.3 (0, 1.4) 0 (0, 0.8) <0.001
Creatinine [mg/dL] 1.2 ± 0.9 1.4 ± 1 0.9 ± 0.6 <0.001
Urine output [mL/d] 2904 ± 1341 2878 ± 1334 2954 ± 1357 0.3841
Urine output [mL/kg/d] 1.5 ± 0.8 1.4 ± 0.7 1.7 ± 0.9 <0.001
Dialysed days 0 (0, 0) 0 (0, 0) 0 (0, 0) 0.2947
Patients with renal replacement therapy [%] 22 24 19 0.1078
Dialysis days/observation days [%] 0 (0, 0) 0 (0, 0) 0 (0, 0) 0.2348