Table 3.
Disease severity of patients with septic shock with regard to sex.
| Characteristics | All (n = 373) |
Male (n = 237) |
Female (n = 136) |
p-Value |
|---|---|---|---|---|
| Sepsis Severity | ||||
| Sequential Organ Failure Assessment (SOFA) | 9 ± 3.9 | 9.2 ± 3.8 | 8.7 ± 4 | 0.1264 |
| Days in septic shock | 2 (1, 3) | 2 (1, 3) | 2 (1, 4) | 0.1425 |
| ICU length of stay | 24 ± 19 | 23 ± 16 | 25 ± 24 | 0.9666 |
| Hospital length of stay | 42 ± 31 | 43 ± 31 | 40 ± 31 | 0.4649 |
| Inflammatory Values | ||||
| Leukocytes [1000/µL] | 13.9 ± 5.5 | 13.8 ± 5.7 | 14.2 ± 5.2 | 0.3576 |
| C-reactive protein [mg/L] (n = 219) | 156 ± 79 | 160 ± 79 | 147 ± 78 | 0.2204 |
| Procalcitonin [ng/dL] (n = 352) | 1.8 (0.7, 5.9) | 2.2 (0.9, 6.1) | 1.4 (0.5, 5.4) | 0.0804 |
| Respiratory Values | ||||
| SOFA respiratory subscore | 2.2 ± 0.7 | 2.3 ± 0.8 | 2.1 ± 0.7 | 0.1089 |
| Ventilated days | 13 ± 9 | 13 ± 9 | 13 ± 9 | 0.9130 |
| Patients with mechanical ventilation [%] | 97 | 97 | 96 | 0.8788 |
| Ventilation days/observation days [%] | 74 ± 29 | 75 ± 29 | 73 ± 30 | 0.8123 |
| Coagulation | ||||
| SOFA coagulation subscore | 0.2 (0, 0.9) | 0.2 (0, 1) | 0.3 (0, 0.9) | 0.9773 |
| Thrombocytes [1000/µL] | 251 ± 142 | 257 ± 154 | 240 ± 118 | 0.7232 |
| Liver Values | ||||
| SOFA hepatic subscore | 0.1 (0, 1) | 0.1 (0, 0.9) | 0.1 (0, 1) | 0.6701 |
| Bilirubin [mg/dL] | 0.8 (0.5, 1.6) | 0.8 (0.5, 1.6) | 0.7 (0.4, 1.7) | 0.1118 |
| AST (GOT) [IU/L] (n = 291) | 69 (40, 140) | 71 (41, 160) | 67 (38, 121) | 0.6234 |
| ALT (GPT) [IU/L] (n = 362) | 44 (22, 101) | 49 (25, 98) | 37 (19, 106) | 0.0964 |
| Cardiovascular Values | ||||
| SOFA cardiovascular subscore | 2.1 ± 1 | 2.1 ± 1 | 2.1 ± 1 | 0.7594 |
| Vasopressor days | 8 ± 6 | 8 ± 6 | 9 ± 7 | 0.7382 |
| Patients with vasopressor treatment [%] | 100 | 100 | 100 | 1.0 |
| Vasopressor days/observation days [%] | 52 ± 30 | 51 ± 30 | 53 ± 30 | 0.5564 |
| Central Nervous System | ||||
| SOFA central nervous system | 2.3 ± 1 | 2.3 ± 1 | 2.3 ± 1 | 0.8255 |
| Glasgow Coma Scale (GCS) | 9 ± 3 | 9 ± 3 | 9 ± 3 | 0.9277 |
| Renal Values | ||||
| SOFA renal subscore | 0.6 (0.1, 2) | 0.8 (0.2, 2.3) | 0.3 (0, 1.3) | 0.0021 |
| Creatinine [mg/dL] | 1.4 ± 1 | 1.6 ± 1 | 1.1 ± 0.7 | <0.001 |
| Urine output [mL/d] | 2661 ± 1540 | 2661 ± 1549 | 2661 ± 1531 | 0.9924 |
| Urine output [mL/kg/d] | 1.4 ± 0.8 | 1.3 ± 0.8 | 1.5 ± 0.9 | 0.0326 |
| Dialysed days | 0 (0, 4) | 0 (0, 4) | 0 (0, 3) | 0.1682 |
| Patients with renal replacement therapy [%] | 39 | 43 | 32 | 0.0503 |
| Dialysis days/observation days [%] | 0 (0, 28) | 0 (0, 33) | 0 (0, 18) | 0.1027 |