Table 2.
Main variable parameters for the fabrication of gelatin-based nanoparticles using the two-step desolvation technique.
| Polymer % (w/v) | Temperature (°C) | Solvent:Non-Solvent Ratio | pH | Crosslinker % (v/v) | Ref. |
|---|---|---|---|---|---|
| 0.06 | 40 | N. d. | 2.5 | GA, 25% | [106] |
| 0.8 | 40 | N. d. | 4.0 | GA, 8% | [81] |
| 2.0 | 40 | 1:3 | 3.0–11.0 | GA, 25% | [78] |
| 2.0 | 40 | 1:3 | <4.8, 9.2–9.4 | GA, 25% | [77] |
| 2.0 | 40 | 1:3 | 3.0 | GA, 25% | [110] |
| 3.0 | 40 | N. d. | 8.5 | CaCl2, 1 M | [105] |
| 5.0 | 40 | 1:1.6 | 3.0 | GA, 25% | [86] |
| 5.0 | N. d. | 1:1.6 | 2.5 | GA, 8% | [108] |
| 5.0 | 40 | 1:3 | 2.5 | GA, 25% | [107] |
| 5.0 | 50 | 1:3 | 2.5 | GA, 25% | [100] |
| 5.0 | 50 | 1:3 | 2.5–12.0 | GA, 25% | [79] |
| 5.0 | 35–37 | 1:1 | N. d. | GA, 25% | [84] |
| 5.0 | 40 | 1:3 | 2.5–12.0 | GA, 25% | [76] |
| 7.7 | 40 | 1:3 | 11.0 | GA, 25% | [109] |
| 9.0 | 40 | 1:3 | 3.0 | GA, 25% | [111] |