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. 2023 May 15;15(5):1499. doi: 10.3390/pharmaceutics15051499

Table 3.

Main variable parameters for the fabrication of gelatin-based nanoparticles using nanoprecipitation technique.

Polymer % (w/v) Solvent:Non-Solvent Ratio Non-Solvent Stabilizer %
(w/v)
Crosslinker %
(w/v)
Ref.
0.80–3.41 1:15 Ethanol 0.80–3.41
Tween 80
GA, 5.0% [102]
0.90 1:1.5 Ethanol 0.03
Lutrol F68
GA, 0.5% [90]
1.25 1:20 Ethanol 2.00
Pluronic F-127
GA, 5.0% [113]
1.25 1:20 Ethanol 2.00
Pluronic F-127
GA, 5.0% [82]
1.25 1:10 Acetone 4.00
Poloxamer 407
GA, 2.0% [80]
2.00 1:15 Acetone 3.00
Poloxamer 188
Diisopropylcarbodiimide, 1.50% [95]
2.00 1:15 Acetone 2.8
Poloxamer 188
GA, 2.0% [69]
2.00 1:15 Ethanol 4.27
Pluronic F-127
GA, 5.0% [113]
0.2 1:10 Ethanol 7.00
Lutrol F127
GA, 2.0% [114]
4.00 1:6 Acetone-dimethyl formamide [111]