Table 10.
Summary table of applications and outcomes obtained with the use of loaded gelatin microparticles/nanoparticles in clinical studies.
| Issue | Bioactive Compound | Outcome(s) | Ref. |
|---|---|---|---|
| Chronic venous leg ulcers | Keratinocytes | Fast healing and complete regeneration. | [200] |
| Vitiligo | Melanocytes | Complete repigmentation, no adverse events. | [201] |
| Sun protection | Ruthin | Increased free-radical-scavenging rate. | [109] |
| Metastatic liver tumors | Cisplatin | Reduction in tumor size, no serious side effects. | [194] |
| Hepatocellular carcinoma | Cisplatin | No serious side effects, 100% success rate, reduced abdominal pain. | [195] |
| Limb ischemia | bFGF | Complete or partial regression of ischemic ulcers, no local and systemic effects. | [196] |
| Peripheral arterial disease | bFGF | Improvement in symptoms and no serious complications, incomplete necrosis or ulcer healing. | [198] |
| Fingertip amputation | bFGF | No statistically significative improvements. | [199] |
| Limb ischemia | bFGF | No serious adverse events. | [197] |