Table 1.
BCS Class | Solubility | Permeability | Drug Molecule Examples |
---|---|---|---|
I | High | High | Mefoquine hydrochloride, Nelfnavir mesylate, Quinine sulfate, Clomiphene citrate |
II | Low | High | Ibuprofen, Nifedipine, Carbamazepine, Diazepam, Efavirenz |
III | High | Low | Amiloride hydrochloride, Amoxicillin, Ethosuximide, Fluconazole, Isoniazid, Salbutamol |
IV | Low | Low | Acetazolamide, Dapsone, Doxycycline, Nalidixic acid, Theophylline |