Table 2.

Factors affecting solubility.

S. No	Factors Affecting Solubility	Details	References
1.	Particle size	As particle size is reduced, the surface area will increase, and the larger surface area will provide a greater interaction of the solute molecules with the solvent.	[34]
2.	Temperature	Solubility will be increased when the temperature rises and the solution process absorbs energy; if the solution process generates energy, then solubility will decrease with an increase in temperature.	[35]
3.	Pressure	Pressure will only affect the solubility of gaseous solutes and have no effect on solid and liquid solutes. A decrease in pressure causes a decrease in solubility, and an increase in pressure causes an increase in the solubility of gaseous solutes.	[35]
4.	Nature of solute and solvent	Properties of solute, as well as the solvent, have drastic effects on solubility.	[36]
5.	Polarity	Substances with the same type of polarity will be soluble in one another, “similia similibus solvuntur”. Polar solute molecules or ions will dissolve in polar solvents, while non-polar solute molecules will dissolve in non-polar solvents.	[37]
6.	Polymorphism	Polymorphs differ in melting points. Different polymorphs have different solubilities as solubility and melting point are linked.	[38]
7.	Stirring	Stirring ensures that new solvent components come into contact with the solid and liquid solutes, resulting in increasing solubility.	[39]