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. Author manuscript; available in PMC: 2023 May 27.
Published in final edited form as: Mod Pathol. 2021 Sep 7;35(1):44–51. doi: 10.1038/s41379-021-00911-w

Fig. 3. HER2 tumor status classification using annotated slides.

Fig. 3

AUC/ROC for HER2 status classification at the slide-level (a) and at the tile-level (b) for both transfer learning and the fully trained models. c Tile-level AUC of the three-way classifiers. d Two representative H&E slides from the test set with corresponding heatmaps based on predicted probabilities by the CNN model. Yellow regions indicate the ROIs determined by our pathology team. The middle panel shows predicted heatmaps for unannotated model and the right panel shows the predicted heatmaps from three-way annotated model.