Table 2.
Logistic regression-Symptoms in the fourth wave compared to the first 3.
| Variables | Wave | p | OR (95% CI) | |||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |||
| Cough | 32 (59.3) | 120 (45.1) | 55 (21.1) | 249 (22.1) | <0.001 | 0.47 (0.26–0.84) |
| Fever | 39 (72.2) | 136 (51.1) | 78 (29.9) | 220 (19.5) | <0.001 | 0.33 (0.19–0.57) |
| Pharyngitis | 5 (9.3) | 49 (18.4) | 38 (14.6) | 307 (27.2) | 0.01 | 2.26 (1.16–4.40) |
| Rhinitis | 2 (3.7) | 50 (18.8) | 69 (26.4) | 287 (25.4) | 0.049 | 1.22 (0.67–2.22) |
| Flu syndrome | 22 (40.7) | 56 (21.1) | 25 (9.6) | 35 (3.1) | <0.001 | 0.12 (0.053–0.30) |
| Headache | 30 (55.6) | 53 (20.0) | 53 (20.3) | 164 (14.5) | 0.03 | 0.51 (0.27–0.95) |
| Anosmia | 27 (50.0) | 83 (31.3) | 24 (9.2) | 18 (1.6) | <0.001 | 0.044 (0.017–0.11) |
| Ageusia | 25 (46.3) | 76 (28.7) | 23 (8.8) | 14 (1.2) | <0.001 | 0.037 (0.014–0.1) |
| Asthenia | 23 (42.6) | 39 (14.7) | 33 (12.6) | 99 (8.8) | 0.43 | 0.74 (0.35–1.57) |
| Conjunctivitis | 9 (16.7) | 5 (1.9) | 6 (2.3) | 5 (0.4) | 0.05 | 0.15 (0.02–1.02) |
| Arthralgia/Arthritis | 20 (37.0) | 68 (25.7) | 25 (9.6) | 48 (4.3) | <0.001 | 0.17 (0.073–0.39) |
| Myalgia | 17 (31.5) | 83 (31.3) | 26 (10.0) | 57 (5.0) | <0.001 | 0.23 (0.10–0.54) |
| Diarrhea | 9 (16.7) | 22 (8.3) | 7 (2.7) | 15 (1.3) | 0.05 | 0.23 (0.05–1.05) |
| Abdominal Pain | 3 (5.6) | 6 (2.3) | 0 (0.0) | 1 (0.1) | 0.54 | 0.081 (0.00–277.27) |
| Nausea | 6 (11.1) | 4 (1.5) | 6 (2.3) | 9 (0.8) | 0.28 | 0.37 (0.06–2.24) |
| Vomiting | 1 (1.9) | 1 (0.4) | 3 (1.1) | 5 (0.4) | 0.99 | 1.005 (0.065–15.48) |
| Dyspnea | 8 (14.8) | 10 (3.8) | 4 (1.5) | 9 (0.8) | 0.22 | 0.28 (0.038–2.15) |
| Pneumonia | 1 (1.9) | 2 (0.8) | 0 (0.0) | 0 (0.0) | 0.99 | 0.000 (0.0–0.0) |
| Asymptomatic | 5 (9.3) | 53 (19.9) | 68 (26) | 401 (35.5) | <0.001 | 1.83 (1.02–3.28) |
| Number of symptoms | ||||||
| 0 | 5 (9.3) | 53 (19.9) | 68 (26) | 401 (35.5) | <0.001 | 1 |
| 1–3 | 15 (27.8) | 101 (38.3) | 162 (62.1) | 652 (57.8) | 0.76 (0.60–0.97) | |
| ≥4 | 34 (63) | 110 (41.7) | 31 (11.9) | 76 (6.7) | 0.14 (0.10–0.20) | |