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. 2023 May 18;15(5):1523. doi: 10.3390/pharmaceutics15051523

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Cytotoxicity of the Fe₃O₄/Cur@ALG and Fe₃O₄@ALG NPs on sarcoma 180 cells. (A) The uptake of Fe₃O₄/Cur@ALG into sarcoma 180 cells can be seen based on the green autofluorescence signal of curcumin after 48 h of incubation with different concentrations of Fe. Cell nuclei were stained with Hoechst, and the cytoskeleton was visualized using microtubule staining (in red). (B) The proliferation of sarcoma 180 cells after 48 h of incubation with the two types of NPs. Data are presented as the mean ± SD of triplicate experiments. Scale bar: 5 µm.