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Average crude incidence per quarter of IPD for pre-vaccine (2000–2002), PCV7 era (2003–2010), PCV13 era (2011–2019), SARS-CoV-2 pandemic (2020 and 2021), and late pandemic (2022): (a) in children less than 18 years of age, and (b) in adults 18 years and older.
