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Simvastatin´s dissolution (grey circles) and release from MCM (blue circles) normalized for the total quantity used in the trial (averaged over three trials; error bars are of the order of the data point symbol): (a) As monitored for 56 days (solid lines are a guide for the eyes). (b) scale up of the first 10 h evidencing the superior releasing rate of loaded amorphous SIM compared with the neat crystalline drug dissolution.
