Skip to main content
. 2023 Apr 30;15(5):316. doi: 10.3390/toxins15050316

Table 1.

scFv yeast displayed libraries used for BoNT/G mAb discovery.

Library Name Immunogen
(Days 0, 21, 42)
Boost Immunogen
(Day 63)
Library Size Resulting Antibodies
BoNT/G library Recombinant BoNT/G LC-HN 2 MLD50
BoNT/G holotoxin
2.0 × 107 6G6
BoNT/G LC-HN
library
Recombinant BoNT/G LC-HN Recombinant BoNT/G LC-HN 2.4 × 107 6G7, 6G8
BoNT/Gi library Recombinant BoNT/Gi Recombinant BoNT/Gi 5.0 x 107 13 antibodies
(see Table 2)