Table 1.
Library Name | Immunogen (Days 0, 21, 42) |
Boost Immunogen (Day 63) |
Library Size | Resulting Antibodies |
---|---|---|---|---|
BoNT/G library | Recombinant BoNT/G LC-HN | 2 MLD50 BoNT/G holotoxin |
2.0 × 107 | 6G6 |
BoNT/G LC-HN library |
Recombinant BoNT/G LC-HN | Recombinant BoNT/G LC-HN | 2.4 × 107 | 6G7, 6G8 |
BoNT/Gi library | Recombinant BoNT/Gi | Recombinant BoNT/Gi | 5.0 x 107 | 13 antibodies (see Table 2) |