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. 2023 May 22;11(5):1359. doi: 10.3390/microorganisms11051359

Figure 1.

Figure 1

Protective effects of L. sakei CVL-001 against DSS-induced colitis. (A) Scheme of the experimental design. Mice were randomly divided into six groups (n = 9/group). (B) Body weight changes (%) during the colitis and recovery phases (mean ± SEM) and total weight loss relative to day 0. Statistical indicators (*) were compared with the DSS + PBS group. (C) Disease activity index of mice (mean ± SEM). Statistical indicators (*) were compared with the DSS + PBS group. (D) Macroscopic appearance of representative colons from each group. (E) Quantification of colon length (mean ± SEM). The significance of differences among the DSS-treated groups was assessed using a two-way analysis of variance (ANOVA) for body weight and disease activity index and a Mann–Whitney U test for colon length, with the level of significance set at p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***). SEM, standard error of mean; DSS, dextran sulfate sodium; PBS, phosphate-buffered saline.