Table 2.
Relative number of acidic and basic variants after MFD and storage at the respective temperatures over the course of 6 months for all formulations.
| Formulation Number | Acidic Variants (%) | Basic Variants (%) | ||||||
|---|---|---|---|---|---|---|---|---|
| 0 m | 6 m | 0 m | 6 m | |||||
| 4 °C | 25 °C | 40 °C | 4 °C | 25 °C | 40 °C | |||
| F1 | 24.5 ± 0.6 | 26.9 ± 1.5 | 24.9 ± 1.6 | 25.7 ± 1.4 | 13.7 ± 0.3 | 14.6 ± 0.2 | 13.7 ± 1.0 | 15.5 ± 0.3 |
| F2 | 25.8 ± 0.1 | 27.1 ± 1.4 | 26.1 ± 2.6 | 30.5 ± 1.6 | 13.1 ± 0.3 | 13.0 ± 0.6 | 13.4 ± 0.5 | 20.9 ± 0.7 |
| F3 | 26.0 ± 0.1 | 25.5 ± 1.0 | 26.6 ± 0.6 | 28.3 ± 1.0 | 14.5 ± 0.3 | 13.2 ± 0.2 | 15.1 ± 0.5 | 20.5 ± 0.6 |
| F4 | 24.3 ± 0.6 | 26.6 ± 2.2 | 26.3 ± 2.9 | 28.1 ± 2.4 | 11.0 ± 0.6 | 13.5 ± 0.4 | 14.2 ± 0.4 | 18.2 ± 1.4 |
| F5 | 27.8 ± 0.1 | 29.8 ± 0.3 | 31.0 ± 0.5 | 32.9 ± 0.8 | 11.6 ± 0.6 | 13.5 ± 1.2 | 16.3 ± 0.5 | 25.7 ± 1.8 |
| F6 | 27.2 ± 1.0 | 29.0 ± 1.1 | 31.2 ± 0.4 | 43.7 ± 0.2 | 11.8 ± 1.9 | 12.1 ± 0.4 | 16.4 ± 0.5 | 21.4 ± 0.3 |
The values are means (n = 3) ± standard deviation. m, month.