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P[8], P[6], and P[4]-specific serum antibody responses in Wa HRV-challenged Gn pigs. Serum was collected at PVD 0, 14, 28 (PCD 0), and 35 (PCD 7) to evaluate systemic P-type-specific IgG (A) and IgA (B) responses using direct ELISA. Asterisks indicate degree of statistically significant difference (mixed-effects analysis with Dunnett’s multiple comparisons test; * p ≤ 0.05, *** p ≤ 0.001, **** p ≤ 0.0001). Lines and error bars indicate mean and SEM, respectively.
