Table 4.
Possible Drugs and their corresponding details.
| Human Genes | Drugs | Adjusted p-Value | Drug Bank ID | Treatment |
|---|---|---|---|---|
| ARF1, PPP2R1A, HNRNPH1, P4HB, ACTB | Nitrofural | 0.0052 | DB00336 | Topical antibacterial for the prevention and treatment of bacterial infections of the skin |
| SEC61A1, ARF1, DNAJC7, PCBP1, PSMD2, TECR, CYC1, P4HB, ACTB, PFKP | Clindamycin | 0.0077 | DB01190 | Antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal and pneumococcal bacteria |
| HNRNPH1, PSMD2, NCL, ACTB, ARCN1 | Ipratropium Bromide | 0.0101 | DB00332 | Used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD) |
| ARF1, PRPF6, PPP2R1A, TECR, RPLP2, ACTB | Ambroxol | 0.0130 | DB06742 | Airway secretion clearance therapy |
| ARF1, PPP2R1A, TECR, P4HB, ACTB | Paclitaxel | 0.0133 | DB01229 | Treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer |
| ARF1, PPP2R1A, ACTB | Benserazide | 0.0236 | DB12783 | Treat Parkinson’s disease, Parkinsonism, and restless leg syndrome |
| ARF1, PPP2R1A, HNRNPH1, ACTB | Amikacin | 0.0351 | DB00479 | An aminoglycoside used to treat infections caused by more resistant strains of Gram-negative bacteria and some Gram-positive bacteria |
| ARF1, P4HB, ACTB | Captopril | 0.0420 | DB01197 | An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction and nephropathy |