Table 2.
Blood pressure, heart rate, premature ventricular contractions, and premature atrial contractions over 24 h before and after switching from oral bisoprolol tablets to the bisoprolol transdermal patch.
| Tablet | Patch | p Value | |
|---|---|---|---|
| Systolic blood pressure (mm Hg) | 127 (117, 137.5) | 127.5 (116.5, 141.3) | 0.674 |
| Diastolic blood pressure (mm Hg) | 71.5 (65.8, 81.3) | 73.5 (66, 81) | 0.977 |
| Heart rate | |||
| Minimum (bpm) | 56 (51, 60.5) | 54 (51, 61) | 0.63 |
| Mean (bpm) | 73 (68.5, 80.5) | 72 (66.5, 77) | 0.227 |
| Maximum (bpm) | 115 (102.5, 126) | 112 (97.5, 126) | 0.359 |
| Total (n) | 100,865 (90,907, 109,855) | 96,953 (90,365, 106,020) | 0.467 |
| PVC time segment (h) | |||
| 0–5 | 8 (1, 87) | 4 (0, 24.5) | 0.005 |
| 6–11 | 13 (3, 110) | 8 (5, 32.5) | 0.009 |
| 12–17 | 10 (3, 85) | 13 (1, 58.5) | 0.359 |
| 18–24 | 15 (2, 101) | 15 (1, 42.5) | 0.085 |
| PAC time segment (h) | |||
| 0–5 | 10 (0, 46.5) | 5 (0, 23.5) | 0.07 |
| 6–11 | 8 (0, 56) | 12 (0, 26) | 0.062 |
| 12–17 | 13 (0, 53) | 10 (0, 23.5) | 0.269 |
| 18–24 | 11 (0, 28) | 10 (0, 28.5) | 0.33 |
PACs, premature atrial contractions; PVCs, premature ventricular contractions.