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Kaplan–Meier estimates of time to treatment discontinuation (TD) for different reasons. (A) TD for overall toxicity; (B) TD for central nervous system toxicity; (C) TD for simplification; (D) TD for drug–drug interactions. Abbreviations: ART, antiretroviral therapy; TD, treatment discontinuation; TD-CNS, TD for central nervous system toxicity; TD-DDI, TD for drug–drug interactions; TD-S, TD for simplification.
