Algorithm for management of hypertriglyceridaemia-induced acute pancreatitis. a serum amylase can be inaccurate or normal in HTGP due to lipaemia. b aim to keep CBG between 6.0–10.0 mmol/L. c seek specialist advice before stopping long-term medications. d seek a specialist to advise; decision should be individualised. No evidence of benefit in terms of hard clinical outcomes, i.e., mortality, the severity of pancreatitis, length of hospital stay, and complications. AP: acute pancreatitis; APACHE II: The Acute Physiology and Chronic Health Examination; CTSI: CT severity index; HDU: high-dependency unit; HTG: hypertriglyceridaemia; HTGP: hypertriglyceridaemia-induced pancreatitis; ITU: intensive therapy unit; NBM: nil by mouth; SHTG: severe hypertriglyceridaemia; TG, Triglycerides; VRII: variable-rate insulin infusion.