Table 5.
Risankizumab 360 mg | . | . | 1.17 [0.74; 1.84] |
. | . | . | 1.37 [0.84; 2.22] |
. | . | . | . |
1.03 [0.55; 1.93] |
Guselkumab 1200 mg IV, then 200 mg sc | 1.09 [0.76; 1.56] |
. | . | . | . | 1.32 [0.89; 1.96] |
. | . | . | . |
1.12 [0.60; 2.11] |
1.09 [0.76; 1.56] |
Guselkumab 200 mg sc | . | . | . | . | 1.22 [0.81; 1.83] |
. | . | . | . |
1.17 [0.74; 1.84] |
1.13 [0.59; 2.15] |
1.04 [0.54; 1.99] |
Risankizumab 180 mg | . | . | . | 1.17 [0.71; 1.94] |
. | . | . | . |
1.32 [0.77; 2.25] |
1.28 [0.81; 2.02] |
1.18 [0.73; 1.88] |
1.13 [0.65; 1.97] |
CJM112 | . | . | 1.04 [0.82; 1.31] |
. | . | . | . |
1.33 [0.75; 2.34] |
1.28 [0.78; 2.11] |
1.18 [0.71; 1.97] |
1.14 [0.63; 2.05] |
1.01 [0.69; 1.47] |
Bimekizumab | . | 1.12 [0.76; 1.67] |
0.97 [0.69; 1.37] |
. | . | . |
1.36 [0.83; 2.25] |
1.32 [0.87; 2.00] |
1.22 [0.79; 1.87] |
1.17 [0.69; 1.97] |
1.04 [0.79; 1.35] |
1.03 [0.74; 1.43] |
Secukinumab q2w | 1.00 [0.88; 1.13] |
. | 1.01 [0.89; 1.15] |
. | . |
1.37 [0.84; 2.22] |
1.32 [0.89; 1.96] |
1.22 [0.81; 1.83] |
1.17 [0.71; 1.94] |
1.04 [0.82; 1.31] |
1.03 [0.76; 1.39] |
1.00 [0.88; 1.13] |
Placebo | 1.00 [0.90; 1.11] |
1.01 [0.89; 1.14] |
1.14 [0.89; 1.47] |
1.20 [0.85; 1.71] |
1.37 [0.83; 2.24] |
1.32 [0.88; 1.99] |
1.22 [0.80; 1.86] |
1.17 [0.70; 1.97] |
1.04 [0.80; 1.34] |
1.03 [0.77; 1.39] |
1.00 [0.85; 1.18] |
1.00 [0.90; 1.11] |
Adalimumab | . | . | . |
1.38 [0.84; 2.27] |
1.33 [0.88; 2.02] |
1.23 [0.80; 1.89] |
1.18 [0.70; 1.99] |
1.05 [0.80; 1.36] |
1.04 [0.75; 1.44] |
1.01 [0.89; 1.15] |
1.01 [0.89; 1.14] |
1.01 [0.86; 1.19] |
Secukinumab q4w | . | . |
1.56 [0.91; 2.69] |
1.51 [0.95; 2.41] |
1.39 [0.86; 2.25] |
1.34 [0.76; 2.35] |
1.18 [0.84; 1.67] |
1.18 [0.80; 1.74] |
1.14 [0.87; 1.51] |
1.14 [0.89; 1.47] |
1.14 [0.87; 1.50] |
1.13 [0.86; 1.50] |
Avacopan | . |
1.65 [0.91; 2.99] |
1.59 [0.94; 2.70] |
1.47 [0.86; 2.51] |
1.41 [0.76; 2.61] |
1.25 [0.82; 1.90] |
1.24 [0.78; 1.97] |
1.21 [0.83; 1.75] |
1.20 [0.85; 1.71] |
1.20 [0.83; 1.73] |
1.19 [0.82; 1.73] |
1.05 [0.69; 1.62] |
IFX-1 800 mg Q4w |