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. 2023 Apr 28;15(5):1351. doi: 10.3390/pharmaceutics15051351

Table 5.

League table presenting the NMA results of adverse effects.

Risankizumab 360 mg . . 1.17
[0.74; 1.84]
. . . 1.37
[0.84; 2.22]
. . . .
1.03
[0.55; 1.93]
Guselkumab 1200 mg IV, then 200 mg sc 1.09
[0.76; 1.56]
. . . . 1.32
[0.89; 1.96]
. . . .
1.12
[0.60; 2.11]
1.09
[0.76; 1.56]
Guselkumab 200 mg sc . . . . 1.22
[0.81; 1.83]
. . . .
1.17
[0.74; 1.84]
1.13
[0.59; 2.15]
1.04
[0.54; 1.99]
Risankizumab 180 mg . . . 1.17
[0.71; 1.94]
. . . .
1.32
[0.77; 2.25]
1.28
[0.81; 2.02]
1.18
[0.73; 1.88]
1.13
[0.65; 1.97]
CJM112 . . 1.04
[0.82; 1.31]
. . . .
1.33
[0.75; 2.34]
1.28
[0.78; 2.11]
1.18
[0.71; 1.97]
1.14
[0.63; 2.05]
1.01
[0.69; 1.47]
Bimekizumab . 1.12
[0.76; 1.67]
0.97
[0.69; 1.37]
. . .
1.36
[0.83; 2.25]
1.32
[0.87; 2.00]
1.22
[0.79; 1.87]
1.17
[0.69; 1.97]
1.04
[0.79; 1.35]
1.03
[0.74; 1.43]
Secukinumab q2w 1.00
[0.88; 1.13]
. 1.01
[0.89; 1.15]
. .
1.37
[0.84; 2.22]
1.32
[0.89; 1.96]
1.22
[0.81; 1.83]
1.17
[0.71; 1.94]
1.04
[0.82; 1.31]
1.03
[0.76; 1.39]
1.00
[0.88; 1.13]
Placebo 1.00
[0.90; 1.11]
1.01
[0.89; 1.14]
1.14
[0.89; 1.47]
1.20
[0.85; 1.71]
1.37
[0.83; 2.24]
1.32
[0.88; 1.99]
1.22
[0.80; 1.86]
1.17
[0.70; 1.97]
1.04
[0.80; 1.34]
1.03
[0.77; 1.39]
1.00
[0.85; 1.18]
1.00
[0.90; 1.11]
Adalimumab . . .
1.38
[0.84; 2.27]
1.33
[0.88; 2.02]
1.23
[0.80; 1.89]
1.18
[0.70; 1.99]
1.05
[0.80; 1.36]
1.04
[0.75; 1.44]
1.01
[0.89; 1.15]
1.01
[0.89; 1.14]
1.01
[0.86; 1.19]
Secukinumab q4w . .
1.56
[0.91; 2.69]
1.51
[0.95; 2.41]
1.39
[0.86; 2.25]
1.34
[0.76; 2.35]
1.18
[0.84; 1.67]
1.18
[0.80; 1.74]
1.14
[0.87; 1.51]
1.14
[0.89; 1.47]
1.14
[0.87; 1.50]
1.13
[0.86; 1.50]
Avacopan .
1.65
[0.91; 2.99]
1.59
[0.94; 2.70]
1.47
[0.86; 2.51]
1.41
[0.76; 2.61]
1.25
[0.82; 1.90]
1.24
[0.78; 1.97]
1.21
[0.83; 1.75]
1.20
[0.85; 1.71]
1.20
[0.83; 1.73]
1.19
[0.82; 1.73]
1.05
[0.69; 1.62]
IFX-1 800 mg Q4w