Table 1.
Baseline characteristics, early cFO (at 72 h)
| Demographics | cFO < 5% (N = 59) | cFO > 10% (N = 14) | P-value |
|---|---|---|---|
| Age at OHT, years (mean, sd) | 9.9 (7.0) | 5.3 (6.2) | 0.03 |
| Infant < 1 year at OHT | 12 (20.3%) | 4 (28.6%) | 0.5 |
| Gender | |||
| Male | 30 (50.9%) | 6 (42.9%) | 0.59 |
| Female | 29 (49.2%) | 8 (57.1%) | |
| Race | |||
| Hispanic | 33 (55.9%) | 8 (57.1%) | 0.94 |
| Weight, kg (mean, sd) | 38.9 (27.7) | 19.4 (19.4) | 0.01 |
| Cyanotic lesion | 14 (23.7%) | 7 (50%) | 0.05 |
| Indications for transplant | |||
| Congenital | 12 (20.3%) | 7 (50%) | 0.08 |
| Myocarditis | 2 (3.4%) | 1 (7.1%) | |
| Cardiomyopathy | 38 (64.4%) | 4 (28.6%) | |
| Re-transplant failure | 7 (11.9%) | 2 (14.3%) | |
| Support at transplant | |||
| VAD | 14 (23.7%) | 2 (14.3%) | 0.44 |
| ECLS | 5 (8.5%) | 0 (0%) | 0.26 |
| Vasoactives | 8 (13.6%) | 1 (7.1%) | 0.51 |
| Peri/post-transplant | |||
| Cardiopulmonary bypass (min) (mean, sd) | 113.7 (59.8) | 108.5 (31.5) | 0.75 |
| Aortic cross-clamp (min) (mean, sd) | 68.7 (33.0) | 68.1 (31.5) | 0.95 |
| Donor ischemic (min) (mean, sd) | 194.3 (90.7) | 199.5 (122.0) | 0.87 |
| Max VIS 72H (mean, sd) | 12.0 (5.2) | 17.4 (13.5) | 0.25 |
| Graft failure/postoperative ECLS | 3 (5.1%) | 4 (28.6%) | 0.01 |
Bold values indicate statistical significance (p ≤ 0.05)
Baseline perioperative characteristics of patients with early postoperative cumulative fluid overload (cFO) assessed as cumulative fluid balance up to 72 h following post-cardiac transplantation, compared to those without postoperative cFO at given time period
OHT orthotopic heart transplant, VAD ventricular assist device, ECLS extracorporeal life support, VIS vasoactive inotrope score at 72 h following cardiac transplantation