Table 2.
Baseline characteristics, overall cFO (at 1 week)
| Demographics | cFO < 5% (N = 65) | cFO > 10% (N = 23) | P-value |
|---|---|---|---|
| Age at OHT, yrs (mean, sd) | 11.9 (6.4) | 1.7 (2.3) | < 0.001 |
| Infant < 1 year at OHT | 8 (12.3%) | 14 (60.9%) | < 0.001 |
| Gender | |||
| Male | 30 (46.2%) | 10 (43.5%) | 0.83 |
| Female | 35 (53.9%) | 13 (56.5%) | |
| Race | |||
| Hispanic | 35 (53.9%) | 17 (73.9%) | 0.09 |
| Weight, kg (mean, sd) | 44.4 (25.3) | 9.3 (5.6) | < 0.001 |
| Cyanotic lesion | 15 (23.1%) | 8 (34.5%) | 0.27 |
| Indications for transplant | |||
| Congenital | 10 (15.4%) | 8 (34.8%) | 0.03 |
| Myocarditis | 2 (3.1%) | 2 (8.7%) | |
| Cardiomyopathy | 40 (61.5%) | 13 (56.5%) | |
| Re-transplant failure | 13 (20%) | 0 (0%) | |
| Support at transplant | |||
| VAD | 16 (24.6%) | 3 (13.0%) | 0.25 |
| ECLS | 5 (7.7%) | 1 (4.4%) | 0.58 |
| Vasoactives | 7 (10.8%) | 4 (17.4%) | 0.41 |
| Peri/post-transplant | |||
| Cardiopulmonary bypass (min) (mean, sd) | 114.7 (58.7) | 105.0 (28.9) | 0.46 |
| Aortic cross-clamp (min) (mean, sd) | 70.5 (31.4) | 59.3 (24.5) | 0.12 |
| Donor ischemic (min) (mean, sd) | 188.7 (85.6) | 221.1 (110.5) | 0.18 |
| Max VIS 72H (mean, sd) | 12.1 (5.4) | 15.1 (11.3) | 0.42 |
| Graft failure/postoperative ECLS | 3 (4.6%) | 4 (17.4%) | 0.05 |
Bold values indicate statistical significance (p ≤ 0.05)
Baseline perioperative characteristics of patients with overall postoperative cumulative fluid overload (cFO) assessed as cumulative fluid balance up to 1-week following post-cardiac transplantation, compared to those without postoperative fluid overload without postoperative cFO at given time period
OHT orthotopic heart transplant, VAD ventricular assist device, ECLS extracorporeal life support, VIS vasoactive inotrope score at 72 h following cardiac transplantation