Table 4.

% Fluid overload stratification and hemodynamic profiles

	Early (< 72 h)			Overall (1 week)
	cFO > 10% vs < 5%			cFO > 10% vs < 5%
	N	OR (95% CI)	P-value	N	OR (95% CI)	P-value
RAP > 8 mmHg
≤ 1 month	63	2 (0.4, 10.8)	0.42	74	1.2 (0.3, 4.3)	0.8
3–6 months	62	0.5 (0.1, 2.1)	0.33	77	0.1 (0.01, 0.6)	0.01
12 months	42	0.9 (0.2, 5.5)	0.93	52	0.3 (0.1, 1.7)	0.17
PCWP > 12 mmHg
≤ 1 month	62	1.4 (0.3, 7.6)	0.71	73	0.5 (0.1, 1.6)	0.22
3–6 months	62	0.6 (0.1, 2.7)	0.51	77	0.1 (0.01, 0.6)	0.01
12 months	42	1.1 (0.2, 6.5)	0.93	52	0.2 (0.02, 1.4)	0.96
CI < 2 L/min/m2
≤ 1 month	63	0.3(0.03, 2.2)	0.21	74	0.5 (0.1, 2.0)	0.32
3–6 months	61	0.96 (0.1, 9.1)	0.51	76	1.0 (0.2, 4.0)	0.96
12 months	42	2.3 (0.2, 28.9)	0.52	52	0.9 (0.03, 24.7)	0.93

Bold values indicate statistical significance (p ≤ 0.05)

Both early cumulative fluid overload (assessed at 72 h following post-cardiac transplantation) and overall cFO (assessed at 1 week following post-cardiac transplantation) data are presented with respect to cardiopulmonary filling pressures and cardiac index at respective time points post-cardiac transplantation

Odds of elevated cardiopulmonary filling pressure or low cardiac index were calculated using a logistic regression model and displayed as odd ratios (OR) with 95% confidence interval (CI)

RAP right atrial pressure, PCWP pulmonary capillary wedge pressure, CI cardiac index