Table 3.

Intra hepatic IL 34, MCSF or CD68⁺ TAMs in different clinical features of patients with HBV-HCC (n = 30)

Characteristics	N	IL-34		MCSF		CD68+ TAMs
		Median	p value	Median	p value	Median	p value
HBV-DNA (IU/mL)
< 5*102	15	35.7	< 0.001	122.3	< 0.01	21.5	< 0.05
≥ 5*102	11	49.4		56.3		26.3
HBeAg
HBeAg−	10	45.3	< 0.01	134.7	< 0.05	25.8	Ns
HBeAg+	3	24.6		50.0		23.0
AFP
Normal	14	44.4	Ns	57.2	< 0.05	19.2	< 0.0001
Abnormal	16	43.0		101.2		27.2
Differentiation
≤ II	10	54.9	< 0.05	90.3	ns	16.5	< 0.0001
> II	19	34.8		75.1		26.1
Tumor number
1	22	43.4	ns	89.1	< 0.05	20.1	< 0.0001
≥ 2	7	39.1		46.0		31.7
Tumor size
≤ 5	12	53.9	< 0.0001	66.0	ns	25.0	< 0.001
> 5	17	34.8		88.1		21.0

All datum was *10³ image unites. The reference range of AFP is 0–9 μg/L. The histopathological classification is well described in the published Literature