Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 May 27;14:3069. doi: 10.1038/s41467-023-38554-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a Timeline of the animal study. Sham group: rats underwent thoracotomy only without LAD ligation; MI group: rat underwent LAD ligation, without treatment; iCarP + /Light- group: MI rats received chlorella injection and iCarP implantation, without illumination; iCarP + /Light+ group: MI rats received chlorella injection and iCarP illumination. b Removal of TOF after treatment while chest is closed. c Histological evaluation of therapeutic outcome by in situ photosynthesis: representative TUNEL staining images of hearts sections 3 d after MI (apoptosis); representative Masson’s trichrome staining of rat hearts 28 d after MI (fibrosis); representative immunofluorescence staining images of Cx43 (green), cTnT (red), and nuclei (blue) in LV 28 d after MI (down). Scale bars in TUNEL staining images: black = 5 mm, red = 500 μm, blue = 50 μm, scale bars in other staining images: black = 5 mm, red = 100 μm, white = 2 mm. d–f Quantitative analysis of (d) apoptotic cells, (e) infarct area, and (f) ejection fraction based on TUNEL staining, Masson’s trichrome staining, and day 28 echocardiography, respectively (n = 4 per group). Statistical significance was calculated using one-way ANOVA with Tukey’s posttest and data are presented as means ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001. Source data and exact p-values are provided in the Source Data file.