Table 2.

Protein biomarkers associated with progression of SSc–ILD.

Protein name	UniProt database identifier	Z score	Association with progression	p value
DBNL	Q9UJU6	2.85	Positive	0.004
Uncharacterized protein Fragment 2	A0A0J9YY99	2.38	Positive	0.018
RIN3	Q8TB24	2.22	Positive	0.027
PDCD6	O75340	2.17	Positive	0.030
RNASE3	P12724	2.14	Positive	0.032
KRT2	P35908	2.14	Positive	0.032
IGHV3-49	A0A0A0MS15	2.13	Positive	0.033
Uncharacterized protein Fragment 1	A0A0J9YY99	2.06	Positive	0.040
KRT9	P35527	2.05	Positive	0.041
LYZ	P61626	2.04	Positive	0.042
IGKJ3	A0A0A0MT96	2.03	Positive	0.043
LILRA3	Q8N6C8	3.29	Positive	0.044
PRTN3	P24158	1.99	Positive	0.047
CDH2	P19022	− 2.63	Negative	0.008
NEO1	Q92859	− 2.57	Negative	0.010
A1BG	P04217	− 2.43	Negative	0.015
B3GNT2	Q9NY97	− 2.39	Negative	0.017
ZNF500	ZNF500	− 2.27	Negative	0.023
SERPINF2	P08697	− 2.25	Negative	0.024
BTD	P43251	− 2.23	Negative	0.026
KLKB1	P03952	− 2.19	Negative	0.028
PLG	P00747	− 2.18	Negative	0.029
ANPEP	P15144	− 2.11	Negative	0.035
YBX2	Q9Y2T7	− 2.11	Negative	0.035
PON1	P27169	− 2.11	Negative	0.036
HLA− H	P01893	− 2.09	Negative	0.037
FETUB	Q9UGM5	− 2.04	Negative	0.041
BCHE	P06276	− 2.02	Negative	0.044
ENG	P17813	− 1.99	Negative	0.047