Figure 1.

Structure of CIP4.

(A) Diagram showing CIP4 protein structure. The small bars at the top indicate putative COILs. (+) indicates the location of a putative bipartite NLS. Tandem repeats consisting of 39 amino acid (aa) residues (C4 repeats) are shown as arrows. The amino acid residue positions of several key CIP4 deletion mutant breakpoints are indicated by dots at the top. The position of the serine-rich C terminus is marked.

(B) Sequences of the C4 repeats (C4Rs) and putative NLS. The basic charged residues in the NLS sequences are in boldface. The positions of the first and last amino acids in those sequences are in parentheses.