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. 2023 Mar 14;12(9):10979–10989. doi: 10.1002/cam4.5781

FIGURE 3.

FIGURE 3

Benchmark of molecular profile preservation of normal liver biopsies from patients with cancer. Molecular profile preservation benchmark of snap freezer versus liquid nitrogen. (A) Unsupervised cluster analysis of the phosphoproteome of liver tissue samples of four individual patients shows that patient‐specific profiles can clearly be identified in samples snap frozen in the snap freezer as well as in liquid nitrogen. Color key indicates Z‐scores. (B) Unsupervised cluster analysis of RNA expression of 100 most variable genes shows that three individual patient profiles can be clearly identified using samples processed in both freezing methods. Color key indicates Z‐scores.